A Combination of Radiation and the Hypoxia-Activated Prodrug Evofosfamide (TH-302) is Efficacious against a Human Orthotopic Pancreatic Tumor Model-Reference-Cited by-同舟云学术

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A Combination of Radiation and the Hypoxia-Activated Prodrug Evofosfamide (TH-302) is Efficacious against a Human Orthotopic Pancreatic Tumor Model

Published:2017-10 Issue:5 Volume:10 Page:760-765
ISSN:1936-5233
Container-title:Translational Oncology
language:en
Short-container-title:Translational Oncology

Author:

Hajj Carla,Russell James^ORCID,Hart Charles P,Goodman Karyn A,Lowery Maeve A,Haimovitz-Friedman Adriana^ORCID,Deasy Joseph O.,Humm John L.

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference27 articles.

1. Pancreatic tumors show high levels of hypoxia;Koong;Int J Radiat Oncol Biol Phys,2000

2. Analysis of the intra- and intertumoral heterogeneity of hypoxia in pancreatic cancer patients receiving the nitroimidazole tracer pimonidazole;Dhani;Br J Cancer,2015

3. Measurement of Tumor Hypoxia in Patients with Advanced Pancreatic Cancer Based on 18F-Fluoroazomyin Arabinoside Uptake;Metran-Nascente;J Nucl Med,2016

4. Potent and highly selective hypoxia-activated achiral phosphoramidate mustards as anticancer drugs;Duan;J Med Chem,2008

5. Pharmacokinetics of TH-302: a hypoxically activated prodrug of bromo-isophosphoramide mustard in mice, rats, dogs and monkeys;Jung;Cancer Chemother Pharmacol,2012

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1. Evofosfamide and Gemcitabine Act Synergistically in Pancreatic Cancer Xenografts by Dual Action on Tumor Vasculature and Inhibition of Homologous Recombination DNA Repair;Antioxidants & Redox Signaling;2023-09-01

2. Application of bismuth sulfide based nanomaterials in cancer diagnosis and treatment;Nano Today;2023-04

3. Hypoxia, a Targetable Culprit to Counter Pancreatic Cancer Resistance to Therapy;Cancers;2023-02-15

4. The Tumor Microenvironment in Tumorigenesis and Therapy Resistance Revisited;Cancers;2023-01-06

5. The Role of Imaging Biomarkers to Guide Pharmacological Interventions Targeting Tumor Hypoxia;Frontiers in Pharmacology;2022-07-15

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