Concerning FDA approval of trilaciclib (Cosela) in extensive-stage small-cell lung cancer

Author:

Powell Kerrington,Prasad V

Funder

Arnold Ventures

Publisher

Elsevier BV

Subject

Cancer Research,Oncology

Reference12 articles.

1. Commissioner of the FDA approves drug to reduce bone marrow suppression caused by chemotherapy. U.S. Food and Drug Administration. https://www.fda.gov/news-events/press-announcements/fda-approves-drug-reduce-bone-marrow-suppression-caused-chemotherapy. Published February 12, 2021.

2. CDK4/6 inhibition enhances anti-tumor efficacy of chemotherapy and immune checkpoint inhibitor combinations in preclinical models and enhances T-cell activation in patients with SCLC receiving chemotherapy;Lai;J. Immunother. Cancer,2020

3. Trilaciclib prior to chemotherapy and atezolizumab in patients with newly diagnosed extensive-stage small cell lung cancer: a multicentre, randomised, double-blind, placebo-controlled phase II trial [published online ahead of print, 2020 Dec 21;Daniel;Int. J. Cancer,2020

4. Myelopreservation with the CDK4/6 inhibitor trilaciclib in patients with small-cell lung cancer receiving first-line chemotherapy: a phase Ib/randomized phase II trial;Weiss;Ann. Oncol.,2019

5. Myelopreservation with trilaciclib in patients receiving topotecan for small cell lung cancer: results from a randomized, double-blind, placebo-controlled phase II study;Hart;Adv. Ther.,2021

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