Transcriptomic profiling of gamma ray induced mutants from the CGL1 human hybrid cell system reveals novel insights into the mechanisms of radiation-induced carcinogenesis-Reference-Cited by-同舟云学术

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Transcriptomic profiling of gamma ray induced mutants from the CGL1 human hybrid cell system reveals novel insights into the mechanisms of radiation-induced carcinogenesis

Published:2019-12 Issue: Volume:145 Page:300-311
ISSN:0891-5849
Container-title:Free Radical Biology and Medicine
language:en
Short-container-title:Free Radical Biology and Medicine

Author:

Pirkkanen Jake,Tharmalingam Sujeenthar,Morais Igor H.,Lam-Sidun Daniel,Thome Christopher,Zarnke Andrew M.,Benjamin Laura V.,Losch Adam C.,Borgmann Anthony J.,Sinex Helen Chin,Mendonca Marc S.,Boreham Douglas R.

Funder

Bruce Power

Mitacs

NIH

Publisher

Elsevier BV

Subject

Physiology (medical),Biochemistry

Reference60 articles.

1. Hallmarks of cancer: the next generation;Hanahan;Cell,2011

2. Suppression of tumorigenicity;Klinger;Cytogenet. Cell Genet.,1982

3. Human cell hybrids: analysis of transformation and tumorigenicity;Stanbridge;Science,1982

4. Dissociation of anchorage independence from tumorigenicity in human cell hybrids;Stanbridge;Int. J. Cancer,1980

5. The CGL1 (HeLa x normal skin fibroblast) human hybrid cell line: a history of ionizing radiation induced effects on neoplastic transformation and novel future directions in SNOLAB;Pirkkanen;Radiat. Res.,2017

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1. Phenotypic and transcriptional changes in lens epithelial cells following acute and fractionated ionizing radiation exposure;International Journal of Radiation Biology;2024-01-30

2. Overexpression of FRA1 (FOSL1) Leads to Global Transcriptional Perturbations, Reduced Cellular Adhesion and Altered Cell Cycle Progression;Cells;2023-09-24

3. Genomic Loss and Epigenetic Silencing of the FOSL1 Tumor Suppressor Gene in Radiation-induced Neoplastic Transformation of Human CGL1 Cells Alters the Tumorigenic Phenotype In Vitro and In Vivo;Radiation Research;2023-04-21

4. Identification of Radiation-Induced miRNA Biomarkers Using the CGL1 Cell Model System;Bioengineering;2022-05-16

5. Radiation-Induced Alterations in Proliferation, Migration, and Adhesion in Lens Epithelial Cells and Implications for Cataract Development;Bioengineering;2022-01-12

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