Melatonin ameliorates neurological deficits through MT2/IL-33/ferritin H signaling-mediated inhibition of neuroinflammation and ferroptosis after traumatic brain injury

Author:

Gao Yuan,Wang Tao,Cheng Ying,Wu Yumin,Zhu Luwen,Gu Zhiya,Wu Youzhuang,Cai Luwei,Wu Yimin,Zhang Yidan,Gao Cheng,Li Lili,Li Jing,Li Qianqian,Wang Zufeng,Wang Ying,Wang Fudi,Luo Chengliang,Tao Luyang

Funder

Priority Academic Program Development of Jiangsu Higher Education Institutions

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Natural Science Foundation of Jiangsu Province

National Key Research and Development Program of China

Publisher

Elsevier BV

Subject

Physiology (medical),Biochemistry

Reference65 articles.

1. RIPK1 or RIPK3 deletion prevents progressive neuronal cell death and improves memory function after traumatic brain injury;Wehn;Acta Neuropathol Commun,2021

2. Estimating the global incidence of traumatic brain injury;Dewan;J. Neurosurg.,2018

3. Traumatic brain injury: an overview of epidemiology, pathophysiology, and medical management;Capizzi;Med. Clin.,2020

4. Melatonin rescues the mice brain against cisplatin-induced neurodegeneration, an insight into antioxidant and anti-inflammatory effects;Zakria;Neurotoxicology,2021

5. Melatonin prevents endothelial cell pyroptosis via regulation of long noncoding RNA MEG3/miR-223/NLRP3 axis;Zhang;J. Pineal Res.,2018

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