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Flavonoid GL-V9 induces apoptosis and inhibits glycolysis of breast cancer via disrupting GSK-3β-modulated mitochondrial binding of HKII

  • Published:2020-01 Issue: Volume:146 Page:119-129
  • ISSN:0891-5849
  • Container-title:Free Radical Biology and Medicine
  • language:en
  • Short-container-title:Free Radical Biology and Medicine

Author:

Guo Yongjian,Wei Libin,Zhou Yuxin,Lu Na,Tang Xiaoqing,Li Zhiyu,Wang Xiaotang

Funder

National Science & Technology Major Project

Social Development Project of Jiangsu Provincial Science and Technology Department

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Physiology (medical),Biochemistry

Reference42 articles.

1. Breast cancer statistics, 2017, racial disparity in mortality by state;DeSantis;CA A Cancer J. Clin.,2017

2. On the origin of cancer cells;Warburg;Science,1956

3. The Warburg Effect returns to the cancer stage;Zhivotovsky;Semin. Cancer Biol.,2009

4. High aerobic glycolysis of rat hepatoma cells in culture: role of mitochondrial hexokinase;Bustamante;Proc. Natl. Acad. Sci. U. S. A.,1977

5. Regulation of hexokinase binding to VDAC;Pastorino;J. Bioenerg. Biomembr.,2008

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