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Mild oxidative stress induces S-glutathionylation of STAT3 and enhances chemosensitivity of tumoural cells to chemotherapeutic drugs

  • Published:2013-12 Issue: Volume:65 Page:1322-1330
  • ISSN:0891-5849
  • Container-title:Free Radical Biology and Medicine
  • language:en
  • Short-container-title:Free Radical Biology and Medicine

Author:

Butturini Elena,Carcereri de Prati Alessandra,Chiavegato Giulia,Rigo Antonella,Cavalieri Elisabetta,Darra Elena,Mariotto Sofia

Publisher

Elsevier BV

Subject

Physiology (medical),Biochemistry

Reference35 articles.

1. The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors;Hedvat;Cancer Cell,2009

2. STATs in cancer inflammation and immunity: a leading role for STAT3;Yu;Nat. Rev. Cancer,2009

3. STATs in oncogenesis;Bowman;Oncogene,2000

4. Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention;Buettner;Clin. Cancer Res.,2002

5. Molecular approaches towards the inhibition of the signal transducer and activator of transcription 3 (Stat3) protein;Fletcher;ChemMedChem,2008

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