Distinct mechanisms by which Nrf1 and Nrf2 as drug targets contribute to the anticancer efficacy of cisplatin on hepatoma cells

Author:

Wufuer Reziyamu,Liu Keli,Feng Jing,Wang Meng,Hu Shaofan,Chen Feilong,Lin Shanshan,Zhang YiguoORCID

Funder

National Natural Science Foundation of China

Chongqing University

Publisher

Elsevier BV

Reference56 articles.

1. Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast;Chan;Proc. Natl. Acad. Sci. U.S.A.,1993

2. Molecular and cellular basis for the unique functioning of Nrf1, an indispensable transcription factor for maintaining cell homoeostasis and organ integrity;Zhang;Biochem. J.,2016

3. TCF11 has a potent tumor-repressing effect than its prototypic Nrf1alpha by definition of both similar yet different regulatory profiles, with a striking disparity from Nrf2;Wang;Front. Oncol.,2021

4. Oncogenic activation of Nrf2, though as a master antioxidant transcription factor, liberated by specific knockout of the full-length Nrf1alpha that acts as a dominant tumor repressor;Qiu;Cancers,2018

5. TALENs-directed knockout of the full-length transcription factor Nrf1alpha that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells;Ren;Sci. Rep.,2016

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