Spermidine rescues the deregulated autophagic response to oxidative stress of osteoarthritic chondrocytes

Author:

D'Adamo Stefania,Cetrullo Silvia,Guidotti Serena,Silvestri Ylenia,Minguzzi Manuela,Santi Spartaco,Cattini Luca,Filardo Giuseppe,Flamigni Flavio,Borzì Rosa Maria

Funder

Ministero dell’Istruzione, dell’Università e della Ricerca

Ministero della Salute

University of Bologna, Italy

Fondazione del Monte di Bologna e Ravenna

Publisher

Elsevier BV

Subject

Physiology (medical),Biochemistry

Reference77 articles.

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2. Emerging players at the intersection of chondrocyte loss of maturational arrest, oxidative stress, senescence and low-grade inflammation in osteoarthritis;Minguzzi;Oxid Med Cell Longev,2018

3. The NF-kappaB family of transcription factors and its regulation;Oeckinghaus;Cold Spring Harb Perspect Biol,2009

4. Autophagy and cartilage homeostasis mechanisms in joint health, aging and OA;Lotz;Nat. Rev. Rheumatol.,2011

5. The autophagic response to oxidative stress in osteoarthritic chondrocytes is deregulated;Goutas;Free Radic. Biol. Med.,2018

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