Knockdown delta-5-desaturase promotes the formation of a novel free radical byproduct from COX-catalyzed ω-6 peroxidation to induce apoptosis and sensitize pancreatic cancer cells to chemotherapy drugs
Author:
Funder
NIH
Publisher
Elsevier BV
Subject
Physiology (medical),Biochemistry
Reference57 articles.
1. Endogenous n-3 polyunsaturated fatty acids delay progression of pancreatic ductal adenocarcinoma in Fat-1-p48 (Cre/+)-LSL-Kras (G12D/+) mice;Mohammed;Neoplasia,2012
2. Zhu BT. EPA, an omega-3 fatty acid, induces apoptosis in human pancreatic cancer cells: role of ROS accumulation, caspase-8 activation, and autophagy induction;Fukui;J. Cell Biochem.,2013
3. Omega-3-polyunsaturated fatty acids suppress pancreatic cancer cell growth in vitro and in vivo via downregulation of Wnt/Beta-catenin signaling;Song;Pancreatology,2011
4. Apoptosis in human pancreatic cancer cells induced by eicosapentaenoic acid;Shirota;Nutrition,2005
5. Docosahexaenoic acid induces apoptosis in the human PaCa-44 pancreatic cancer cell line by active reduced glutathione extrusion and lipid peroxidation;Merendino;Nutr. Cancer,2005
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