Nitrite treatment downregulates vascular MMP-2 activity and inhibits vascular remodeling in hypertension independently of its antihypertensive effects

Author:

Rizzi Elen,Amaral Jefferson H.,Guimarães Danielle A.,Conde-Tella Sandra O.,Pinheiro Lucas C.,Gerlach Raquel F.,Castro Michele M.,Tanus-Santos Jose E.

Funder

FAPESP

CNPq

CAPES

Publisher

Elsevier BV

Subject

Physiology (medical),Biochemistry

Reference51 articles.

1. Seventh report of the Joint National committee on prevention, detection, evaluation, and treatment of high blood pressure;Chobanian;Hypertension,2003

2. Inhibition of matrix metalloproteinases (MMPs) as a potential strategy to ameliorate hypertension-induced cardiovascular alterations;Castro;Curr. Drug Targets,2013

3. Prognostic significance of small-artery structure in hypertension;Rizzoni;Circulation,2003

4. Matrix metalloproteinases: targets for doxycycline to prevent the vascular alterations of hypertension;Castro;Pharmacol. Res.,2011

5. Matrix metalloproteinase (MMP)-2 decreases calponin-1 levels and contributes to arterial remodeling in early hypertension;Belo;Biochem. Pharmacol.,2016

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