Menadione inhibits thioredoxin reductase 1 via arylation at the Sec498 residue and enhances both NADPH oxidation and superoxide production in Sec498 to Cys498 substitution
Author:
Funder
Fundamental Research Funds for the Central Universities
National Natural Science Foundation of China
Publisher
Elsevier BV
Subject
Physiology (medical),Biochemistry
Reference47 articles.
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4. Molecular mechanisms of thioredoxin and glutaredoxin as hydrogen donors for Mammalian s phase ribonucleotide reductase;Zahedi Avval;J. Biol. Chem.,2009
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