Kinetic modeling of the synthesis of N-aminopiperidine via the Raschig process: Reaction optimization and continuous process

Author:

Darwich C.,Elkhatib M.,Pasquet V.,Delalu H.

Publisher

Elsevier BV

Subject

Industrial and Manufacturing Engineering,General Chemical Engineering,Environmental Chemistry,General Chemistry

Reference7 articles.

1. C.G. Kruse, J.H.M. Lange, A.H.J. Herremans, H.H. van Stuivenberg, 1H-imidazole derivatives having CB1 partial agonistic or CB1-antagonistic activity, International Patent WO 03027076, 2003.

2. H. Neunhoeffer, S. Gerstung, T. Clausen, W.R. Balzer, Process for the synthesis of 4,5-diaminopyrazole derivatives useful for dyeing hair, US Patent 5663366, 1997.

3. Hydrazine and Its Derivatives: Preparation, Properties, Applications;Schmidt,2001

4. Kinetic and mechanistic study of N-aminopiperidine formation via the Raschig process;Darwich;Kinet. Catal.,2013

5. Kinetics of the oxidation of N-aminopiperidine with chloramine;Darwich;Kinet. Catal.,2009

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