A two-photon fluorescent probe sensitive to NADPH reveals metabolic aberrations in brain cells arising from mitochondrial dysfunction in Alzheimer’s disease
-
Published:2024-09
Issue:
Volume:495
Page:153652
-
ISSN:1385-8947
-
Container-title:Chemical Engineering Journal
-
language:en
-
Short-container-title:Chemical Engineering Journal
Author:
Wang Xueao, Liu Yani, Kim Subin, Zhang Chenrun, Li Zheng, Xu Chen, Zhu Hai-LiangORCID, Qian YongORCID
Reference45 articles.
1. Highly Sensitive Near-Infrared Fluorophores for in Vivo Detection of Amyloid-β Plaques in Alzheimer’s Disease;Fu;Journal of Medicinal Chemistry,2015 2. The amyloid state and its association with protein misfolding diseases;Knowles;Nature Reviews Molecular Cell Biology,2014 3. Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques;Lee;Nature Neuroscience,2022 4. D.-o. Seo, D. O’Donnell, N. Jain, J.D. Ulrich, J. Herz, Y. Li, M. Lemieux, J. Cheng, H. Hu, J.R. Serrano, X. Bao, E. Franke, M. Karlsson, M. Meier, S. Deng, C. Desai, H. Dodiya, J. Lelwala-Guruge, S.A. Handley, J. Kipnis, S.S. Sisodia, J.I. Gordon, D.M. Holtzman, ApoE isoform– and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy, Science 379(6628) eadd1236. 5. F. Bao, L. Zhou, R. Zhou, Q. Huang, J. Chen, S. Zeng, Y. Wu, L. Yang, S. Qian, M. Wang, X. He, S. Liang, J. Qi, G. Xiang, Q. Long, J. Guo, Z. Ying, Y. Zhou, Q. Zhao, J. Zhang, D. Zhang, W. Sun, M. Gao, H. Wu, Y. Zhao, J. Nie, M. Li, Q. Chen, J. Chen, X. Zhang, G. Pan, H. Zhang, M. Li, M. Tian, X. Liu, Mitolysosome exocytosis, a mitophagy-independent mitochondrial quality control in flunarizine-induced parkinsonism-like symptoms, Science Advances 8(15) eabk2376.
|
|