Longitudinal follow-up and characterization of a robust rat model for Parkinson's disease based on overexpression of alpha-synuclein with adeno-associated viral vectors

Author:

Van der Perren Anke,Toelen Jaan,Casteels Cindy,Macchi Francesca,Van Rompuy Anne-Sophie,Sarre Sophie,Casadei Nicolas,Nuber Silke,Himmelreich Uwe,Osorio Garcia Maria Isabel,Michotte Yvette,D'Hooge Rudi,Bormans Guy,Van Laere Koen,Gijsbers Rik,Van den Haute Chris,Debyser Zeger,Baekelandt Veerle

Funder

IWT-Vlaanderen

FWO Vlaanderen

KU Leuven

MJ Fox Foundation

Publisher

Elsevier BV

Subject

Geriatrics and Gerontology,Developmental Biology,Neurology (clinical),Aging,General Neuroscience

Reference80 articles.

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2. Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease;Appel-Cresswell;Mov Disord,2013

3. Phosphorylation does not prompt, nor prevent, the formation of alpha-synuclein toxic species in a rat model of Parkinson's disease;Azeredo da Silveira;Hum Mol Genet,2009

4. Characterization of lentiviral vector-mediated gene transfer in adult mouse brain;Baekelandt;Hum Gene Ther,2002

5. The regulation of synaptic function by alpha-synuclein;Bellani;Commun Integr Biol,2010

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