Genome-wide interaction analysis reveals replicated epistatic effects on brain structure

Author:

Hibar Derrek P.,Stein Jason L.,Jahanshad Neda,Kohannim Omid,Hua Xue,Toga Arthur W.,McMahon Katie L.,de Zubicaray Greig I.,Martin Nicholas G.,Wright Margaret J.,Weiner Michael W.,Thompson Paul M.

Funder

National Institutes of Health

National Institute on Aging

National Institute of Biomedical Imaging and Bioengineering

U.S. National Library of Medicine

National Center for Research Resources

National Institute of Child Health and Human Development

National Health and Medical Research Council

Australian Research Council Future Fellowship

ADNI

Abbott Fund

Alzheimer's Association

Alzheimer Drug Discovery Foundation

Amorfix Life Sciences Ltd

AstraZeneca

Bayer Healthcare

BioClinica, Inc

Biogen

Bristol-Myers Squibb Foundation

Eisai

Elan

Eli Lilly and Company

F. Hoffmann-La Roche Ltd

Genentech Foundation

GE Healthcare

Innogenetics, N.V.

IXICO Ltd

Janssen Alzheimer Immunotherapy Research & Development, LLC

Johnson & Johnson Pharmaceutical Research & Development LLC

Medpace, Inc

Merck & Co, Inc

Meso Scale Diagnostics, LLC

Novartis

Pfizer

Servier

Synarc Inc

Takeda Pharmaceuticals North America

Canadian Institutes of Health Research

Northern California Institute for Research and Education

Publisher

Elsevier BV

Subject

Geriatrics and Gerontology,Developmental Biology,Neurology (clinical),Aging,General Neuroscience

Reference57 articles.

1. A map of human genome variation from population-scale sequencing;Abecasis;Nature,2010

2. Alzheimer's Disease Neuroimaging Initiative. Genetic variation and neuroimaging measures in Alzheimer disease;Biffi;Archives of neurology,2010

3. Common variants at 12q14 and 12q24 are associated with hippocampal volume;Bis;Nature genetics,2012

4. Neuroimaging measures as endophenotypes in Alzheimer’s disease, Int;Braskie;J. Alzheimer’s Dis,2011

5. Recent advances in imaging Alzheimer’s disease;Braskie;J. Alzheimers Dis.,2013

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