Age-dependent effect of APOE and polygenic component on Alzheimer's disease

Author:

Bellou Eftychia,Baker EmilyORCID,Leonenko GannaORCID,Bracher-Smith Matthew,Daunt Paula,Menzies Georgina,Williams Julie,Escott-Price ValentinaORCID

Funder

UK Research and Innovation

Medical Research Council

Publisher

Elsevier BV

Subject

Geriatrics and Gerontology,Developmental Biology,Clinical Neurology,Ageing,General Neuroscience

Reference38 articles.

1. A quarter century of APOE and Alzheimer's disease: progress to date and the path forward;Belloy;Neuron,2019

2. Apolipoprotein E and Alzheimer disease: genotype-specific risks by age and sex;Bickeböller;Am. J. Hum. Genet.,1997

3. ApoE-4 and age at onset of Alzheimer's disease: the NIMH genetics initiative;Blacker;Neurology,1997

4. Age-dependent effects of APOE ε4 in preclinical Alzheimer's disease;Bonham;Ann. Clin. Transl Neurol.,2016

5. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families;Corder;Science,1993

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