Alpha7 nicotinic acetylcholine receptor-specific agonist DMXBA (GTS-21) attenuates Aβ accumulation through suppression of neuronal γ-secretase activity and promotion of microglial amyloid-β phagocytosis and ameliorates cognitive impairment in a mouse model of Alzheimer's disease-Reference-Cited by-同舟云学术

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Alpha7 nicotinic acetylcholine receptor-specific agonist DMXBA (GTS-21) attenuates Aβ accumulation through suppression of neuronal γ-secretase activity and promotion of microglial amyloid-β phagocytosis and ameliorates cognitive impairment in a mouse model of Alzheimer's disease

Published:2018-02 Issue: Volume:62 Page:197-209
ISSN:0197-4580
Container-title:Neurobiology of Aging
language:en
Short-container-title:Neurobiology of Aging

Author:

Takata Kazuyuki,Amamiya Takahide,Mizoguchi Hiroaki,Kawanishi Shohei,Kuroda Eriko,Kitamura Risa,Ito Aina,Saito Yuki,Tawa Manami,Nagasawa Tomofumi,Okamoto Haruka,Sugino Yuko,Takegami Shigehiko,Kitade Tatsuya,Toda Yuki,Kem William R.,Kitamura Yoshihisa,Shimohama Shun,Ashihara Eishi

Funder

MEXT

Japan Society for the Promotion of Science

SRF

Kyoto Pharmaceutical University

YOKOYAMA Foundation for Clinical Pharmacology

SENSHIN Medical Research Foundation

Takeda Science Foundation

KOBAYASHI MAGOBE Memorial Foundation

Publisher

Elsevier BV

Subject

Geriatrics and Gerontology,Developmental Biology,Neurology (clinical),Aging,General Neuroscience

Reference81 articles.

1. Mechanisms of neuroprotective effects of nicotine and acetylcholinesterase inhibitors: role of α4 and α7 receptors in neuroprotection;Akaike;J. Mol. Neurosci.,2010

2. Coupled proliferation and apoptosis maintain the rapid turnover of microglia in the adult brain;Askew;Cell Rep.,2017

3. A cell surface receptor complex for fibrillar β-amyloid mediates microglial activation;Bamberger;J. Neurosci.,2003

4. Clinical and biomarker changes in dominantly inherited Alzheimer's disease;Bateman;N. Engl. J. Med.,2012

5. Nicotine addiction: the possible role of functional upregulation;Buisson;Trends Pharmacol. Sci.,2002

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