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A novel pathway for amyloid precursor protein processing

Published:2011-06 Issue:6 Volume:32 Page:1090-1098
ISSN:0197-4580
Container-title:Neurobiology of Aging
language:en
Short-container-title:Neurobiology of Aging

Author:

Portelius Erik,Price Eric,Brinkmalm Gunnar,Stiteler Mark,Olsson Maria,Persson Rita,Westman-Brinkmalm Ann,Zetterberg Henrik,Simon Adam J.,Blennow Kaj

Publisher

Elsevier BV

Subject

Geriatrics and Gerontology,Developmental Biology,Clinical Neurology,Ageing,General Neuroscience

Reference29 articles.

1. ADAMs family members as amyloid precursor protein alpha-secretases;Allinson;J. Neurosci. Res.,2003

2. Cerebrospinal fluid beta-amyloid(1–42) in Alzheimer disease: differences between early- and late-onset Alzheimer disease and stability during the course of disease;Andreasen;Arch. Neurol.,1999

3. Generation of C-terminally truncated amyloid-beta peptides is dependent on gamma-secretase activity;Beher;J. Neurochem.,2002

4. Aph-1, Pen-2, and nicastrin with presenilin generate an active gamma-secretase complex;De Strooper;Neuron,2003

5. Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain;Dovey;J. Neurochem.,2001

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