Lentiviral vector–mediated overexpression of Klotho in the brain improves Alzheimer's disease–like pathology and cognitive deficits in mice-Reference-Cited by-同舟云学术

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Lentiviral vector–mediated overexpression of Klotho in the brain improves Alzheimer's disease–like pathology and cognitive deficits in mice

Published:2019-06 Issue: Volume:78 Page:18-28
ISSN:0197-4580
Container-title:Neurobiology of Aging
language:en
Short-container-title:Neurobiology of Aging

Author:

Zeng Chen-Ye,Yang Ting-Ting,Zhou Hong-Jing,Zhao Yue,Kuang Xi,Duan Wei,Du Jun-Rong

Funder

National Science Foundation of China

Sichuan Province Youth Science and Technology Innovation Team

National Ministry of Education

Publisher

Elsevier BV

Subject

Geriatrics and Gerontology,Developmental Biology,Neurology (clinical),Aging,General Neuroscience

Reference49 articles.

1. APP/PS1 mice overexpressing SREBP-2 exhibit combined Abeta accumulation and tau pathology underlying Alzheimer's disease;Barbero-Camps;Hum. Mol. Genet.,2013

2. Klotho, stem cells, and aging;Bian;Clin. Interv. Aging.,2015

3. Klotho is a substrate for alpha-, beta- and gamma-secretase;Bloch;FEBS. Lett.,2009

4. Mammalian target of rapamycin: a valid therapeutic target through the autophagy pathway for Alzheimer's disease?;Cai;J. Neurosci. Res.,2012

5. The relevance of alpha-KLOTHO to the central nervous system: some key questions;Cararo-Lopes;Ageing. Res. Rev.,2017

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2. The association between klotho and kidney and cardiovascular outcomes: a comprehensive systematic review and meta-analysis;Clinical Kidney Journal;2024-08-23

3. Klotho: molecular mechanisms and emerging therapeutics in central nervous system diseases;Molecular Biology Reports;2024-08-17

4. SVHRSP Alleviates Age-Related Cognitive Deficiency by Reducing Oxidative Stress and Neuroinflammation;Antioxidants;2024-05-21

5. Enhanced Therapeutic Effects of Human Mesenchymal stem Cells Transduced with Secreted Klotho in a Murine Experimental Autoimmune Encephalomyelitis Model;Molecular Neurobiology;2024-05-10

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