Genotoxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)

Author:

Wiencke John K.,Wiemels Joseph

Publisher

Elsevier BV

Subject

Toxicology,Genetics

Reference128 articles.

1. Cellular resistance to chloroethyl-nitrosoureas, nitrogen mustard, and cis-diaminedichloroplatinum(II) in human glial-derived cell lines;Aida;Cancer Res.,1987

2. Effect of caffeine on cytotoxicity and sister chromatid exchange induction in sensitive and resistant rat brain tumor cells treated with 1,3-bis(2-chloroethyl)-1-nitrosourea;Aida;Cancer Res.,1987

3. Inhibition of O6-alkylguanine-DNA-alkyltransferase activity potentiates cytotoxicity and induction of SCEs in human glioma cells resistant to 1,3-bis(2-chloroethyl)-1-nitrosourea;Aida;Carcinogenesis,1987

4. Quenching of DNA cross-link precursors of chloroethylnitrosoureas and attenuation of DNA interstrand cross-linking by glutathione;Ali-Osman;Cancer Res.,1989

5. Decreased DNA interstrand cross-linking and cytotoxicity induced in human brain tumor cells by 1,3-bis(2-chloroethyl)-1-nitrosourea after in vitro reaction with glutathione;Ali-Osman;Cancer Res.,1989

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