α-1 Adrenergic receptor antagonist doxazosin reverses hepatic stellate cells activation via induction of senescence

Author:

Serna-Salas Sandra A.ORCID,Arroyave-Ospina Johanna C.ORCID,Zhang Mengfan,Damba TurtushikhORCID,Buist-Homan Manon,Muñoz-Ortega Martin H.,Ventura-Juárez JavierORCID,Moshage Han

Funder

Consejo Nacional de Ciencia y Tecnología

Publisher

Elsevier BV

Subject

Developmental Biology,Aging

Reference39 articles.

1. Regulation of p21/CIP1/WAF-1 mediated cell-cycle arrest by RNase L and tristetraprolin, and involvement of AU-rich elements;Al-Haj;Nucleic Acids Res.,2012

2. Senescence-associated secretory phenotype in a mouse model of bleomycin-induced lung injury;Aoshiba;Exp. Toxicol. Pathol.,2013

3. Soluble egg antigens of Schistosoma japonicum induce senescence in activated hepatic stellate cells by activation of the STAT3/p53/p21 pathway;Chen;Sci. Rep.,2016

4. Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor;Coppé;PLoS Biol.,2008

5. The Senescence-Associated Secretory: the dark side of tumor suppression;Coppé;Annu. Rev. Pathol.,2010

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