Metformin mitigates stress-induced premature senescence by upregulating AMPKα at Ser485 phosphorylation induced SIRT3 expression and inactivating mitochondrial oxidants
Author:
Funder
National Research Foundation of Korea
NRF
Publisher
Elsevier BV
Subject
Developmental Biology,Aging
Reference78 articles.
1. Mitochondria, oxidants, and aging;Balaban;Cell,2005
2. Premature cell senescence in human skin: Dual face in chronic acquired pigmentary disorders;Bellei;Ageing Res. Rev.,2020
3. Extension of life-span by introduction of telomerase into normal human cells;Bodnar;Science,1998
4. Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria;Bridges;Biochem. J.,2014
5. Sirtuin function in aging heart and vessels;Cencioni;J. Mol. Cell Cardiol.,2015
Cited by 13 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Telomere stabilization by metformin mitigates the progression of atherosclerosis via the AMPK-dependent p-PGC-1α pathway;Experimental & Molecular Medicine;2024-09-02
2. New insight into molecular mechanisms of different polyphenols affecting Sirtuin 3 deacetylation activity;International Journal of Biological Macromolecules;2024-06
3. Relevance of real-time analyzers to determine mitochondrial quality in endothelial cells and oxidative stress in preeclampsia;Vascular Pharmacology;2024-06
4. Metformin: From Diabetes to Cancer—Unveiling Molecular Mechanisms and Therapeutic Strategies;Biology;2024-04-27
5. Cellular senescence in acute kidney injury: Target and opportunity;Biochemical and Biophysical Research Communications;2024-04
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3