Membrane Tethered Delta Activates Notch and Reveals a Role for Spatio-Mechanical Regulation of the Signaling Pathway
Author:
Publisher
Elsevier BV
Subject
Biophysics
Reference46 articles.
1. Cell contact-dependent signaling;Fagotto;Dev. Biol.,1996
2. The molecular logic of Notch signaling—a structural and biochemical perspective;Gordon;J. Cell Sci.,2008
3. A conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibition;Cordle;Nat. Struct. Mol. Biol.,2008
4. Structure of the Notch1-negative regulatory region: implications for normal activation and pathogenic signaling in T-ALL;Gordon;Blood,2009
5. Direct observation of proteolytic cleavage at the S2 site upon forced unfolding of the Notch negative regulatory region;Stephenson;Proc. Natl. Acad. Sci. USA,2012
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