Cytotoxicity, sister-chromatid exchanges and DNA single-strand breaks induced by 4-oxo-4-(3-pyridyl)butanal, a metabolite of a tobacco-specific N-nitrosamine

Author:

Alaoui-Jamali M.A.,Gagnon R.,El Alami N.,Castonguay A.

Publisher

Elsevier BV

Subject

Genetics,Toxicology

Reference49 articles.

1. Synthesis of 5′-carboxy-N′-nitrosonornicotine and 5′-([14C]-carboxy)-N′-nitrosonornicotine;Abbaspour;J. Org. Chem.,1987

2. SCE as an index of mutagenesis and/or carcinogenesis;Abe,1982

3. In vitro genotoxicity of 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone activated by hamster maternal and fetal tissues;Alaoui-Jamali;Carcinogenesis,1988

4. Genetic and cytogenetical effects of formaldehyde and related compounds;Auerbach;Mutation Res.,1977

5. Accumulation of DNA adducts in hepatic and respiratory tissue following multiple administrations of the tobacco specific carcinogen 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK);Belinsky,1985

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