Eukaryotic DNA repair is blocked at different steps by inhibitors of DNA topoisomerases and of DNA polymerases α and β
Author:
Publisher
Elsevier BV
Subject
Genetics,Biochemistry,Biophysics,Structural Biology
Reference33 articles.
1. DNA Repair in Bacteria and Mammalian Cells
2. Novobiocin; an inhibitor of the repair of UV-induced but not X-ray-induced damage in mammalian cells
3. Dependence of mammalian DNA synthesis on DNA supercoiling. III Characterization of the inhibition of replicative and repair-type DNA synthesis by novobiocin and nalidixic acid
4. Detection and repair of single-strand breaks in nuclear DNA
5. Type II DNA topoisomerases: Enzymes that can unknot a topologically knotted DNA molecule via a reversible double-strand break
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1. Influence of novobiocin on g-irradiation G0-lymphocytes as analyzed by cytogenetic endpoints;Genetics and Molecular Biology;1999-06
2. Macrostatin, A Novel Macromolecular Inhibitor of Topoisomerases Produced byStreptomyces a VermitilisNo. C-127;Journal of Enzyme Inhibition;1998-01
3. Using Yeast to Understand Drugs that Target Topoisomerases;Annals of the New York Academy of Sciences;1996-12
4. Possible involvement of DNA-repair events in the transdifferentiation of mesophyll cells ofZinnia elegans into tracheary elements;Journal of Plant Research;1995-09
5. Phase I and pharmacologic study of the alkylating agent modulator novobiocin in combination with high-dose chemotherapy for the treatment of metastatic breast cancer.;Journal of Clinical Oncology;1995-05
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