Quinoxaline chemistry. Part 15. 4-[2-Quinoxalylmethylenimino]-benzoylglutamates and -benzoates, 4-[2-quinoxalylmethyl-N-methylamino]-benzoylglutamates as analogues of classical antifolate agents. Synthesis, elucidation of structures and in vitro evaluation of antifolate and anticancer activities

Author:

Loriga Mario,Piras Sandra,Paglietti Giuseppe,Costi Maria Paola,Venturelli Alberto

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmaceutical Science

Reference30 articles.

1. Quinoxaline chemistry: Part 4. 2-(R)-Anilinoquinoxalines as non classic antifolate agents. Synthesis, structure elucidation and evaluation of in vitro anticancer activity;Loriga;Farmaco,1997

2. Quinoxaline chemistry. Part 5. 2-(R)-Benzymamminoquinoxalines as non classical antifolate agents. Synthesis and evaluation of in vitro anticancer activity;Loriga;Farmaco,1996

3. Quinoxaline chemistry. Part 7. 2-[Aminobenzoates]- and 2[Aminobenzoylglutamate]-quinoxalines as classical antifolate agents. Synthesis and evaluation of in vitro anticancer, anti-HIV and antifungal activity;Loriga;Farmaco,1997

4. Quinoxaline chemistry. Part 8. 2-[Anilino]-3-[carboxy]-6(7)-substituted quinoxalines as non classical antifolate agents. Synthesis and evaluation of in vitro anticancer, anti-HIV and antifungal activity;Loriga;Farmaco,1997

5. Quinoxaline chemistry. Part 9. Quinoxaline analogues of TMQ and 10-propargyl-5,8-dideaza folic acid and its precursors. Synthesis and evaluation of in vitro anticancer activity;Vitale;Farmaco,1998

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