Active elimination of the marine biotoxin okadaic acid by P-glycoprotein through an in vitro gastrointestinal barrier

Author:

Ehlers Anke,These Anja,Hessel Stefanie,Preiss-Weigert Angelika,Lampen Alfonso

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference38 articles.

1. Functional characterization of peptide transporters in MDCKII-MDR1 cell line as a model for oral absorption studies;Agarwal;International Journal of Pharmaceutics,2007

2. Mutation-Induction by okadaic acid, a protein phosphatase inhibitor, in CHL cells, but not in Salmonella typhimurium;Aonuma;Mutation Research,1991

3. Study of possible combined toxic effects of azaspiracid-1 and okadaic acid in mice via the oral route;Aune;Toxicon,2012

4. Validation of the Caco-2 cell monolayer system for determining the permeability of drug substances according to the Biopharmaceutics Classification System (BCS);Bock,2003

5. Regulation of cytochrome-P450Ia1 gene-expression in a human intestinal-cell line, Caco-2;Boulenc;Journal of Pharmacology and Experimental Therapeutics,1992

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