P12-06 Establishment of a new transgenic HepaRG cell line expressing CYP2D6: new means for in vitro toxicity assessment of xenobiotics hydroxylated by CYP2D6-Reference-Cited by-同舟云学术

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P12-06 Establishment of a new transgenic HepaRG cell line expressing CYP2D6: new means for in vitro toxicity assessment of xenobiotics hydroxylated by CYP2D6

Published:2024-09 Issue: Volume:399 Page:S201-S202
ISSN:0378-4274
Container-title:Toxicology Letters
language:en
Short-container-title:Toxicology Letters

Author:

Coppens-Exandier H.,Roshchina F.,Ribault C.,Mackanga F.,Schaefer E.,Pelletier R.,Gicquel T.,Chesné C.,Corlu A.,Jamin A.,Loyer P.

Publisher

Elsevier BV

Reference5 articles.

1. Interindividual variability in gene expression profiles in human hepatocytes and comparison with HepaRG cells;Rogue;Drug Metab Dispos.,2012

2. Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells;Aninat;Drug Metab Dispos.,2006

3. Production of chlorzoxazone glucuronides via cytochrome P4502E1 dependent and independent pathways in human hepatocytes;Quesnot;Arch Toxicol,2018

4. Highly efficient SiRNA and gene transfer into hepatocyte-like HepaRG cells and primary human hepatocytes: new means for drug metabolism and toxicity studies;Laurent;Methods Mol Biol.,2013

5. Liposome-Mediated Gene Transfer in Differentiated HepaRG™ Cells: Expression of Liver Specific Functions and Application to the Cytochrome P450 2D6 Expression;Vlach;Cells,2022

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