Urinary metabolite excretion after oral dosage of bis(2-propylheptyl) phthalate (DPHP) to five male volunteers – Characterization of suitable biomarkers for human biomonitoring

Author:

Leng Gabriele,Koch Holger M.,Gries Wolfgang,Schütze Andre,Langsch Angelika,Brüning Thomas,Otter Rainer

Funder

German Chemicals Industry

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference31 articles.

1. A twenty-volunteer study using deuterium labelling to determine the kinetics and fractional excretion of primary and secondary urinary metabolites of di-2-ethylhexylphthalate and di-iso-nonylphthalate;Anderson;Food Chem. Toxicol.,2011

2. BfR Opinion No., 004/2012 of 28 June 2011, http://www.bfr.bund.de/cm/349/dphp-detected-in-toys-bfr-assessing-the-risk-of-the-softener.pdf.

3. Bhat, V.S., Durham, J.L., Ball, G.L., English, J.C., 2014. Derivation of an oral reference dose (RfD) for the plasticizer, di-(2-propylheptyl) phthalate (Palatinol® 10-P), (in press).

4. An Introduction to Pharmacokinetics,1986

5. Commission Regulation (EU) No 10/2011, Official Journal of the European Union L 12/1, 2011.

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