Dietary administration in rodent studies distorts the tissue deposition profile of lanthanum carbonate; brain deposition is a contamination artefact?

Author:

Damment Stephen J.P.,Cox Alan G.,Secker Roger

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference25 articles.

1. Cognitive function in stage 5 chronic kidney disease patients on hemodialysis: no adverse effects of lanthanum carbonate compared with standard phosphate-binder therapy;Altmann;Kidney Int.,2007

2. Localization of lanthanum in bone of chronic renal failure rats after oral dosing with lanthanum carbonate;Behets;Kidney Int.,2005

3. Hepatocellular transport and gastrointestinal absorption of lanthanum in chronic renal failure;Bervoets;Kidney Int.,2008

4. A model of the kinetics of lanthanum in human bone, using data collected during the clinical development of the phosphate binder lanthanum carbonate;Bronner;Clin. Pharmacokinet.,2008

5. Committee for Medicinal Products for Human Use (CHMP), 2005. [EMEA/CPMP/SWP/1094/04] Guideline on the evaluation of control samples in nonclincial safety studies; checking for contamination with the test substance. European Medicines Agency.

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