Molecular determinants of binding of non-oxime bispyridinium nerve agent antidote compounds to the adult muscle nAChR-Reference-Cited by-同舟云学术

Molecular determinants of binding of non-oxime bispyridinium nerve agent antidote compounds to the adult muscle nAChR

Published:2021-04 Issue: Volume:340 Page:114-122
ISSN:0378-4274
Container-title:Toxicology Letters
language:en
Short-container-title:Toxicology Letters

Author:

Epstein Max^ORCID,Bali Karan,Piggot Thomas J.^ORCID,Green A. Christopher,Timperley Christopher M.,Bird Mike,Tattersall John E.H.,Bermudez Isabel,Biggin Philip C.^ORCID

Funder

Engineering and Physical Sciences Research Council

Biotechnology and Biological Sciences Research Council

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference38 articles.

1. Role of the cys loop and transmembrane domain in the allosteric modulation of α4β2 nicotinic acetylcholine receptors;Alcaino;J. Biol. Chem.,2017

2. Studies on the repetitive discharges evoked in motor nerve and skeletal muscle after injection of anticholinesterase drugs;Blaber;Br. J. Pharmacol. Chemother.,1963

3. Mechanisms of neuromuscular block;Cookson;Anaesthesia,1969

4. Nerve agents: what they are, how they work, how to counter them;Costanzi;ACS Chem. Neurosci.,2018

5. Particle mesh Ewald - an N.log(N) method for Ewald sums in large systems;Darden;J. Chem. Phys.,1993

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