Inhibition of an organophosphate-detoxifying bacterial phosphotriesterase by albumin and plasma thiol components

Author:

Köhler Anja,Job LauraORCID,Worek FranzORCID,Skerra Arne

Funder

Bundesamt für Ausrüstung, Informationstechnik und Nutzung der Bundeswehr

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference42 articles.

1. Cysteamine: an old drug with new potential;Besouw;Drug Discov. Today,2013

2. Enzymatic neutralization of the chemical warfare agent VX: evolution of phosphotriesterase for phosphorothiolate hydrolysis;Bigley;J. Am. Chem. Soc.,2013

3. Variants of phosphotriesterase for the enhanced detoxification of the chemical warfare agent VR;Bigley;Biochemistry,2015

4. Structure, properties, and engineering of the major zinc binding site on human albumin;Blindauer;J. Biol. Chem.,2009

5. Evaluation of Enzyme Inhibitors in Drug Discovery. A Guide for Medicinal Chemists and Pharmacologists: Chapter 3: Reversible Modes of Inhibitior Interactions With Enzymes;Copeland,2005

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