Possible role of hepatic macrophage recruitment and activation in triptolide-induced hepatotoxicity

Author:

Wang Lu,Xu Dengqiu,Li Liping,Xing Xin,Liu Li,Ismail Abdelmotalab Mohammed,Xiao Li,Pang Tao,Huang Xin,Wang Xinzhi,Wang Tao,Jiang ZhenzhouORCID,Zhang Luyong,Sun Lixin

Funder

National Natural Science Foundation of China

Specific Fund for Public Interest Research of Traditional Chinese Medicine, the Ministry of Finance

National “Major Scientific and Technological Special Project for Significant New Drugs Creation”

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference42 articles.

1. Liver macrophages in healthy and diseased liver;Abdullah;Pflugers Arch.,2017

2. The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota;Balmer;Sci. Transl. Med.,2014

3. Macrophage migration inhibitory factor contributes to ethanol-induced liver injury by mediating cell injury, steatohepatitis, and steatosis;Barnes;Hepatology,2013

4. The protective effects of Isoliquiritigenin and glycyrrhetinic acid against triptolide-induced oxidative stress in HepG2 cells involve Nrf2 activation;Cao;Evid. Complement. Altern. Med.,2016

5. Distinct bone marrow-derived and tissue-resident macrophage lineages proliferate at key stages during inflammation;Davies;Nat. Commun.,2013

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