Meloxicam methyl group determines enzyme specificity for thiazole bioactivation compared to sudoxicam-Reference-Cited by-同舟云学术

Meloxicam methyl group determines enzyme specificity for thiazole bioactivation compared to sudoxicam

Published:2021-03 Issue: Volume:338 Page:10-20
ISSN:0378-4274
Container-title:Toxicology Letters
language:en
Short-container-title:Toxicology Letters

Author:

Barnette Dustyn A.,Schleiff Mary A.,Datta Arghya,Flynn Noah,Swamidass S. Joshua,Miller Grover P.

Funder

National Institute of General Medical Sciences

U.S. National Library of Medicine

National Institutes of Health

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference46 articles.

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3. Recent applications of 1, 3-thiazole core structure in the identification of new lead compounds and drug discovery;Ayati;Eur. J. Endocrinol.,2015

4. Comprehensive kinetic and modeling analyses revealed CYP2C9 and 3A4 determine terbinafine metabolic clearance and bioactivation;Barnette;Biochem. Pharmacol.,2019

5. Dual mechanisms suppress meloxicam bioactivation relative to sudoxicam;Barnette;Toxicology,2020

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