Testis dysfunction by isoproterenol is mediated by upregulating endothelin receptor A, leptin and protein kinase Cɛ and is attenuated by an endothelin receptor antagonist CPU0213

Author:

Cheng Yu-Si,Dai De-Zai,Dai Yin

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Toxicology

Reference43 articles.

1. Association between mental stress and some antioxidant enzymes of seminal plasma;Eskiocak;Indian J Med Res,2005

2. Effect of emotional stress on sperm quality;Collodel;Indian J Med Res,2008

3. Clinical relevance of oxidative stress and sperm chromatin damage in male infertility: an evidence based analysis;Cocuzza;Int Braz J Urol,2007

4. Effects of CPU 86017 (chlorobenzyltetrahydroberberine chloride) and its enantiomers on thyrotoxicosis-induced overactive endothelin-1 system and oxidative stress in rat testes;Tang;Urology,2006

5. CPU0213, a novel endothelin receptor antagonist, suppresses the upregulation of matrix metalloproteinases and connexin 43 in hyperthyroid myocardium;Tang;Pharmacol Rep,2008

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