Assessment of placental transfer and the effect on embryo-fetal development of a humanized monoclonal antibody targeting lymphotoxin-alpha in non-human primates

Author:

Wang Hong,Schuetz Chris,Arima Akihiro,Chihaya Yutaka,Weinbauer Gerhard F.,Habermann Gunnar,Xiao Jim,Woods Cynthia,Grogan Jane,Gelzleichter Thomas,Cain Gary

Publisher

Elsevier BV

Subject

Toxicology

Reference40 articles.

1. Inhibition of the lymphotoxin pathway as a therapy for autoimmune disease;Browning;Immunol. Rev.,2008

2. Targeted depletion of lymphotoxin-α-expressing TH1 and TH17 cells inhibits autoimmune disease;Chiang;Nat. Med.,2009

3. Lymphotoxin-alpha-deficient mice. Effects on secondary lymphoid organ development and humoral immune responsiveness;Banks;J. Immunol.,1995

4. Abnormal development of secondary lymphoid tissues in lymphotoxin beta-deficient mice;Alimzhanov;Proc. Natl. Acad. Sci. U. S. A.,1997

5. Selective disruption of lymphotoxin ligands reveals a novel set of mucosal lymph nodes and unique effects on lymph node cellular organization;Rennert;Int. Immunol.,1997

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