Hydroxyurea embryotoxicity is enhanced in P53-deficient mice
Author:
Funder
Canadian Institutes of Health Research
Publisher
Elsevier BV
Subject
Toxicology
Reference53 articles.
1. Modes of p53 regulation;Kruse;Cell,2009
2. Editor’s highlight: hydroxyurea exposure activates the P53 signaling pathway in murine organogenesis-stage embryos;El Husseini;Toxicol. Sci.,2016
3. p53 accumulates in micronuclei after treatment with a DNA breaking chemical, methylnitrosourea, and with the spindle poison, vinblastine;Granetto;Mutat. Res.,1996
4. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours;Donehower;Nature,1992
5. p53 mutations in human cancers;Hollstein;Science.,1991
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