Replacement of in vivo acute oral toxicity studies by in vitro cytotoxicity methods: Opportunities, limits and regulatory status

Author:

Ukelis Ute,Kramer Peter-Jürgen,Olejniczak Klaus,Mueller Stefan O.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference50 articles.

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3. Expression of cytochromes p450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells;Aninat;Drug. Metab. Dispos.,2006

4. Anon, 2001. White Paper on a Strategy for a Future Chemicals Policy. Commission of the European Communities, Brussels. Available from: .

5. The biochemical and cellular basis of cell proliferation assays that use tetrazolium salts;Berridge;Biochemica,1996

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