Physiologically based pharmacokinetic combined JAK2 occupancy modelling to simulate PK and PD of baricitinib with kidney transporter inhibitors and in patients with hepatic/renal impairment

Author:

Wang Zhongjian,Liu Wei,Li Xueyan,Chen Hongjiao,Qi Dongying,Pan Fulu,Liu Huining,Yu Shuang,Yi Bowen,Wang Guopeng,Liu YangORCID

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference48 articles.

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2. Nano-encapsulation and characterization of baricitinib using poly-lactic-glycolic acid co-polymer;Ansari;Saudi Pharmaceut. J.,2019

3. Physiologically based pharmacokinetic models of probenecid and furosemide to predict transporter mediated drug-drug interactions;Britz;Pharm. Res. (N. Y.),2020

4. Pharmacogenomics of statins: lipid response and other outcomes in Brazilian cohorts;Dagli-Hernandez;Pharmacol. Rep.,2021

5. de Witte WEA, Danhof M, van der Graaf PH, de Lange ECM. In Vivo Target Residence Time and Kinetic Selectivity: the Association Rate Constant as Determinant. (1873-3735 (Electronic)).

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