An alternative approach for the safety evaluation of new and existing chemicals, an exercise in integrated testing

Author:

Gubbels-van Hal W.M.L.G.,Blaauboer B.J.,Barentsen H.M.,Hoitink M.A.,Meerts I.A.T.M.,van der Hoeven J.C.M.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference18 articles.

1. Absorption classification of oral drugs based on molecular surface properties;Bergström;J. Med. Chem.,2003

2. The necessity of biokinetic information in the interpretation of in vitro toxicity data;Blaauboer;Altern. Lab. Anim.,2002

3. Physiological parameter values for physicologically based pharmacokinetic models;Brown;Tox. Ind. Health,1997

4. A quantative property–property relationship (QPPR) approach to estimate in vitro tissue–blood partition coefficients of organic chemicals in rats and humans;DeJongh;Arch. Toxicol.,1997

5. Dutch Health Council, 2001. Onderzoek Gezondheidsrisico’s Stoffen: een gerichtere Benadering. Gezondheidsraad, Den Haag 2001; publication no. 2001/24.

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