Acute toxicity, twenty-eight days repeated dose toxicity and genotoxicity of vanadyl trehalose in kunming mice

Author:

Jiang Pingzhe,Ni Zaizhong,Wang Bin,Ma Baicheng,Duan Huikun,Li Xiaodan,Ma Xiaofeng,Wei Qian,Ji Xiangzhen,Liu Qiqi,Xing Shuguang,Li Minggang

Funder

Key Technologies R&D Program

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference40 articles.

1. Vanadium induces dopaminergic neurotoxicity via protein kinase Cdelta dependent oxidative signaling mechanisms: relevance to etiopathogenesis of Parkinson's disease;Afeseh Ngwa;Toxicol. Appl. Pharmacol.,2009

2. Time and dose-response study of the effects of vanadate on rats: morphological and biochemical changes in organs;al-Bayati;J. Environ. Patho, Toxicol.Oncolo : official organ Int. Soc. Environ. Toxicol. Cancer,1989

3. Synthesis of a new vanadyl(IV) complex with trehalose (TreVO): insulin-mimetic activities in osteoblast-like cells in culture;Barrio;J. Biolo. Inorg. Chem : JBIC : a Publ. Soc. Biol. Inorg. Chem.,2003

4. Vanadium in the detection, prevention and treatment of cancer: the in vivo evidence;Bishayee;Cancer Lett.,2010

5. Vanadate treatment of diabetic rats reverses the impaired expression of genes involved in hepatic glucose metabolism: effects on glycolytic and gluconeogenic enzymes, and on glucose transporter GLUT2;Brichard;Mol. Cell. Endocrinol.,1993

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