DeepAmes: A deep learning-powered Ames test predictive model with potential for regulatory application

Author:

Li Ting,Liu Zhichao,Thakkar Shraddha,Roberts Ruth,Tong Weida

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference48 articles.

1. Tensorflow: Large-Scale Machine Learning on Heterogeneous Distributed Systems;Abadi,2016

2. Methods for Detecting Carcinogens and Mutagens with the Salmonella/mammalian-microsome Mutagenicity Test;Ames,1975

3. Mechanisms of chemical carcinogenicity and mutagenicity: a review with implications for predictive toxicology;Benigni;Chem. Rev.,2011

4. Bagging predictors;Breiman;Mach. Learn.,1996

5. Evaluation of QSAR models for the prediction of ames genotoxicity: a retrospective exercise on the chemical substances registered under the EU REACH regulation;Cassano;J. Environ. Sci. Health Part C,2014

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