Acute and chronic toxicity in Sprague–Dawley rats of orally-administered total lignans from Arctii Fructus, a potential therapeutic drug for diabetes
Author:
Funder
Science and Technology Commission of Shanghai Municipality
Publisher
Elsevier BV
Subject
Toxicology,General Medicine
Reference20 articles.
1. Arctii Fructus is hypoglycemic and good for back and joints. Fujian;Chen;J. Tradit. Chin. Med.,1999
2. Change in plasma lactate co-ncentration during arctigenin administration in a phase I clinical trial in patie-nts with gemcitabine refractory pancreatic cancer;Fujioka;PLoS One,2018
3. The effects of hypoglycemia and weight loss of total lignans from Fructus Arctii in KKAy mice and its mechanisms of the activity;Gao;Phytother Res.,2018
4. The extract of Arctium lappa L. Fruit (arctii fructus) improves cancer-induced cachexia by inhibiting weight loss of skeletal muscle and adipose tissue;Han;Nutrients,2020
5. Study on acute toxicity of arctigenin and burdock seed extract;He;Chin. J. Vet. Drug.,2019
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