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Minimum datasets to establish a CAR-mediated mode of action for rodent liver tumors

  • Published:2018-07 Issue: Volume:96 Page:106-120
  • ISSN:0273-2300
  • Container-title:Regulatory Toxicology and Pharmacology
  • language:en
  • Short-container-title:Regulatory Toxicology and Pharmacology

Author:

Peffer Richard C.,LeBaron Matthew J.,Battalora Michael,Bomann Werner H.,Werner Christoph,Aggarwal Manoj,Rowe Rocky R.,Tinwell Helen

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference76 articles.

1. Dose-response approaches for nuclear receptor-mediated modes of action for liver carcinogenicity: results of a workshop;Andersen;Crit. Rev. Toxicol.,2014

2. Significance of hepatic preneoplasia in risk identification and early detection of neoplasia;Bannasch;Toxicol. Pathol.,2003

3. The adverse outcome pathway for rodent liver tumor promotion by sustained activation of the aryl hydrocarbon receptor;Becker;Regul. Toxicol. Pharmacol.,2015

4. IPCS framework for analyzing the relevance of a cancer mode of action for humans;Boobis;Crit. Rev. Toxicol.,2006

5. Tumor promotion and inhibition by phenobarbital in livers of conditional Apc-deficient mice;Braeuning;Arch. Toxicol.,2016

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