Consumer product in vitro digestion model: Bioaccessibility of contaminants and its application in risk assessment

Author:

Brandon Esther F.A.,Oomen Agnes G.,Rompelberg Cathy J.M.,Versantvoort Carolien H.M.,van Engelen Jacqueline G.M.,Sips Adrienne J.A.M.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference27 articles.

1. Bremmer, H.J., Van Veen, M.P., 2002. Report No. 612810012. National Institute for Public Health and the Environment, Bilthoven, The Netherlands. Available at: .

2. Physicochemical and physiological mechanisms for the effects of food on drug absorption: the role of lipids and pH;Charman;J. Pharm. Sci.,1997

3. Commission Directive COM 2005 (143), 2005. Restrictions on the marketing and use of certain dangerous substances and preparations (phthalates) and amending council Directive 88/378/EEC on the approximation of the laws of the Member States concerning the safety of toys (COM (1999) 577—C5—0276/1999—1999/0238 (COD)).

4. Commission Directive 1999/815/EC, 1999. 1999/815/EC: Commission Decision of 7 December 1999 adopting measures prohibiting the placing on the market of toys and childcare articles intended to be placed in the mouth by children under three years of age made of soft PVC containing one or more of the substances di-iso-nonyl phthalate (DINP), di(2-ethylhexyl) phthalate (DEHP), dibutyl phthalate (DBP), di-iso-decyl phthalate (DIDP), di-n-octyl phthalate (DNOP), and butylbenzyl phthalate (BBP). L315, pp. 46–49.

5. Commission Directive 93/11/EEC, 1993. Commission Directive 93/11/EEC of 15 March 1993 concerning the release of the N-nitrosamines and N-nitrosatable substances from elastomer or rubber teats and soothers. L093, pp. 37–38.

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