A cross-industry collaboration to assess if acute oral toxicity (Q)SAR models are fit-for-purpose for GHS classification and labelling-Reference-Cited by-同舟云学术

A cross-industry collaboration to assess if acute oral toxicity (Q)SAR models are fit-for-purpose for GHS classification and labelling

Published:2021-03 Issue: Volume:120 Page:104843
ISSN:0273-2300
Container-title:Regulatory Toxicology and Pharmacology
language:en
Short-container-title:Regulatory Toxicology and Pharmacology

Author:

Bercu Joel,Masuda‐Herrera Melisa J.,Trejo-Martin Alejandra^ORCID,Hasselgren Catrin,Lord Jean,Graham Jessica,Schmitz Matthew^ORCID,Milchak Lawrence,Owens Colin,Lal Surya Hari,Robinson Richard Marchese,Whalley Sarah,Bellion Phillip,Vuorinen Anna,Gromek Kamila,Hawkins William A.,van de Gevel Iris,Vriens Kathleen,Kemper Raymond,Naven Russell^ORCID,Ferrer Pierre,Myatt Glenn J.

Funder

National Institutes of Health

National Institute of Environmental Health Sciences

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference48 articles.

1. 16 CFR 1500.3. Code of Federal Regulations. Federal hazardous substances Act (FHSA) requirements. https://www.cpsc.gov/Business--Manufacturing/Business-Education/Business-Guidance/FHSA-Requirements.

2. 49 CFR, Part 178. Code of Federal Regulations. Title: part 178 - specifications for packagings. https://www.govinfo.gov/content/pkg/CFR-2019-title49-vol3/xml/CFR-2019-title49-vol3-part178.xml.

3. Extending (Q)SARs to incorporate proprietary knowledge for regulatory purposes: a case study using aromatic amine mutagenicity;Ahlberg;Regul. Toxicol. Pharmacol.,2016

4. Leveraging heterogeneous data from GHS toxicity annotations, molecular and protein target descriptors and Tox21 assay readouts to predict and rationalise acute toxicity;Allen;J. Cheminf.,2019

5. Principles and procedures for implementation of ICH M7 recommended (Q)SAR analyses;Amberg;Regul. Toxicol. Pharmacol.,2016

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