The OSIRIS Weight of Evidence approach: ITS mutagenicity and ITS carcinogenicity

Author:

Buist Harrie,Aldenberg Tom,Batke Monika,Escher Sylvia,Klein Entink Rinke,Kühne Ralph,Marquart Hans,Pauné Eduard,Rorije Emiel,Schüürmann Gerrit,Kroese Dinant

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference40 articles.

1. Multiple test in silico weight-of-evidence for toxicological endpoints;Aldenberg,2010

2. Batke, M., Aldenberg, T., Escher, S., Mangelsdorf, I., 2012. Relevance of non-guideline studies for risk assessment: the coverage model based on most frequent targets in repeated dose toxicity studies. Toxicology Letters, http://dx.doi/org/10.1016/j.toxlet.2012.09.002 [Epub ahead of print].

3. Structure alerts for carcinogenicity and the Salmonella assay system: a novel insight through the chemical relational database technology;Benigni;Mutat. Res.,2008

4. Structural analysis and predictive value of the rodent in vivo micronucleus assay results;Benigni;Mutagenesis,2010

5. Caesar, 2011. Computer Assisted Evaluation of industrial chemical Substances According to Regulations. News & Updates. Mutagenicity v2.0 available for download. Website http://www.caesar-project.eu/. Software available from: .

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