Implications of dose-dependent target tissue absorption for linear and non-linear/threshold approaches in development of a cancer-based oral toxicity factor for hexavalent chromium

Author:

Haney J.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference15 articles.

1. EWG, 2010. Chromium-6 in US Tap Water. Environmental Working Group, December 20, 2010. Available at: http://static.ewg.org/reports/2010/chrome6/chrome6_report_2.pdf.

2. Use of dose-dependent absorption into target tissues to more accurately predict cancer risk at low oral doses of hexavalent chromium;Haney;Regul. Toxicol. Pharmacol.,2015

3. Physiologically based pharmacokinetic model for rats and mice orally exposed to chromium;Kirman;Chem. Biol. Interact.,2012

4. Physiologically based pharmacokinetic model for humans orally exposed to chromium;Kirman;Chem. Biol. Interact.,2013

5. An evaluation of the mode of action framework for mutagenic carcinogens case study II: chromium(VI);McCarroll;Environ. Mol. Mutagen.,2010

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