Influence of ligand binding to human cytochrome P-450 1A2: conformational activation and stabilization by α-naphthoflavone
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,Biochemistry,Biophysics,Structural Biology
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4. Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines.
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1. 2-Amino-3,8-Dimethylimidazo[4,5-f ]Quinoxaline (MeIQx)–Induced Hepatocarcinogenesis Is Not Enhanced by CYP1A Inducers, Alpha- and Beta-Naphthoflavone;Toxicologic Pathology;2010-05-06
2. How does dextran sulfate prevent heat induced aggregation of protein?: The mechanism and its limitation as aggregation inhibitor;Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics;2007-02
3. Highly Miniaturized Formats for In Vitro Drug Metabolism Assays Using Vivid® Fluorescent Substrates and Recombinant Human Cytochrome P450 Enzymes;Journal of Biomolecular Screening;2005-02
4. Electrochemical study of the interaction between cytochrome P450sccK201E and cholesterol;Talanta;2004-04
5. Tight-binding inhibition by α-naphthoflavone of human cytochrome P450 1A2;Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics;2003-05
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