Two naturally occurring mutations in the kinase domain of insulin receptor accelerate degradation of the insulin receptor and impair the kinase activity.-Reference-Cited by-同舟云学术

Two naturally occurring mutations in the kinase domain of insulin receptor accelerate degradation of the insulin receptor and impair the kinase activity.

Published:1994-12 Issue:49 Volume:269 Page:31019-31027
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Imamura T,Takata Y,Sasaoka T,Takada Y,Morioka H,Haruta T,Sawa T,Iwanishi M,Hu Y G,Suzuki Y

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference53 articles.

1. Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

2. The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling

3. Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

4. Lilly Lecture: Molecular Mechanisms of Insulin Resistance: Lessons From Patients With Mutations in the Insulin-Receptor Gene

5. Human Diabetes Associated with a Mutation in the Tyrosine Kinase Domain of the Insulin Receptor

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